Diazepam onset

Diazepam onset

• A. 30-60 mins
• B. 1-5 mins (IV), 1-20 (IM)
• C. 5-10 mins
• D. 15-30 mins

Answer: (B)

Diazepam’s onset depends on how quickly it enters the bloodstream and reaches the brain. Intravenous administration bypasses absorption barriers, giving CNS effects within about 1–5 minutes. If given intramuscularly, absorption from muscle is slower, leading to onset roughly in the range of 1–20 minutes. Oral diazepam has the slowest onset due to digestion, absorption, and first-pass metabolism, typically around 30–60 minutes. So the fastest and most reliable onset is with IV 1–5 minutes, followed by IM around 1–20 minutes, which is why that option best fits.

Diazepam’s onset depends on how quickly it enters the bloodstream and reaches the brain. Intravenous administration bypasses absorption barriers, giving CNS effects within about 1–5 minutes. If given intramuscularly, absorption from muscle is slower, leading to onset roughly in the range of 1–20 minutes. Oral diazepam has the slowest onset due to digestion, absorption, and first-pass metabolism, typically around 30–60 minutes. So the fastest and most reliable onset is with IV 1–5 minutes, followed by IM around 1–20 minutes, which is why that option best fits.